How would you create a system that offers more healthcare, to more people, at lower prices and high quality? What if you designed it purely around the needs of patients? This question drove Dr. Adam Oskowitz and Matt Pavelle to build Doctronic. Not just another healthcare app, but a first-principles reimagining of direct-to-consumer care in an AI-native world. They've created a system offering private, personalized care available 24/7 across all states, powered by better information processin...

How would you create a system that offers more healthcare, to more people, at lower prices and high quality? What if you designed it purely around the needs of patients? This question drove Dr. Adam Oskowitz and Matt Pavelle to build Doctronic. Not just another healthcare app, but a first-principles reimagining of direct-to-consumer care in an AI-native world. They've created a system offering private, personalized care available 24/7 across all states, powered by better information processin...

This blog is co-authored with Zoe Weinberg and Matt Hawes at ex/ante and can also be found here. Who will own our digital memory? This question has become increasingly urgent as ChatGPT and Claude ask us to entrust more and more of our memories to their platforms. Frontier AI models have already ingested the world's public knowledge, but their advancements may slow down as we approach a compute ceiling. Additional performance gains will require them to adapt to the user’s context, which calls...

This blog is co-authored with Zoe Weinberg and Matt Hawes at ex/ante and can also be found here. Who will own our digital memory? This question has become increasingly urgent as ChatGPT and Claude ask us to entrust more and more of our memories to their platforms. Frontier AI models have already ingested the world's public knowledge, but their advancements may slow down as we approach a compute ceiling. Additional performance gains will require them to adapt to the user’s context, which calls...

AI represents something fundamental and powerful: an entirely new computing paradigm that will reshape how we work, learn, and interact. But today's AI landscape offers limited options: either access AI models through commercial APIs or use "open source" models released by large tech companies. Neither approach fully addresses the opportunity for broader participation in AI development. As we wrote in our recent Four Futures post on where AI might head, we believe that there is an opportunity...

AI represents something fundamental and powerful: an entirely new computing paradigm that will reshape how we work, learn, and interact. But today's AI landscape offers limited options: either access AI models through commercial APIs or use "open source" models released by large tech companies. Neither approach fully addresses the opportunity for broader participation in AI development. As we wrote in our recent Four Futures post on where AI might head, we believe that there is an opportunity...

The Information Age was a consequence of two developments: the ability to work with information programmatically and the democratization of that capability. We are now entering a similar period in biology. We can now program life itself with the ever cheaper tools of synthetic biology. We believe this era of programmable biology will spark a new wave of entrepreneurs who push the limits of what biology can do.

The Information Age was a consequence of two developments: the ability to work with information programmatically and the democratization of that capability. We are now entering a similar period in biology. We can now program life itself with the ever cheaper tools of synthetic biology. We believe this era of programmable biology will spark a new wave of entrepreneurs who push the limits of what biology can do.

When we invested in 3Box Labs in 2021, we expressed a thesis that the future of data infrastructure would move from siloed, proprietary databases to open, composable data networks. We saw how this shift would enable developers to build data-rich applications more quickly by leveraging existing networks of data and standards. Today, that vision takes another step forward with the launch of Recall, a project born from the recent merger of 3Box Labs and Textile. Recall extends the concept of com...

When we invested in 3Box Labs in 2021, we expressed a thesis that the future of data infrastructure would move from siloed, proprietary databases to open, composable data networks. We saw how this shift would enable developers to build data-rich applications more quickly by leveraging existing networks of data and standards. Today, that vision takes another step forward with the launch of Recall, a project born from the recent merger of 3Box Labs and Textile. Recall extends the concept of com...

This blog is co-authored with Zoe Weinberg and Matt Hawes at ex/ante, and is a follow-up to our first blog post on the topic, 'You don't own your memory.' We need an open architecture that puts us in control of our memories while making their exploitation technically impossible. But how will this shift happen? In order to discover possible implementations, we must understand how our data informs LLMs. The three predominant context engineering techniques are prompt design, retrieval-augmented ...

This blog is co-authored with Zoe Weinberg and Matt Hawes at ex/ante, and is a follow-up to our first blog post on the topic, 'You don't own your memory.' We need an open architecture that puts us in control of our memories while making their exploitation technically impossible. But how will this shift happen? In order to discover possible implementations, we must understand how our data informs LLMs. The three predominant context engineering techniques are prompt design, retrieval-augmented ...

We’re excited by tools that retrieve, move, and process data with elegance. But we’re interested in partnering with tools that turn this data into collective knowledge and sources of truth. Despite a wildly changing landscape, systems of record continue to be the door to endurance.

We’re excited by tools that retrieve, move, and process data with elegance. But we’re interested in partnering with tools that turn this data into collective knowledge and sources of truth. Despite a wildly changing landscape, systems of record continue to be the door to endurance.